HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoroacetic acid → HCID 178452374, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | HCID 178452368 | HCID 178452368 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 178452374 | HCID 178452374 | — |
Reaction Steps
To a solution of 146 mg 4-[(S)-2-tert-Butoxycarbonylamino-3-(3-hydroxy-5-methyl-isoxazol-4-yl)-propionyl]-piperazine-1-carboxylic acid butyl ester in 5 ml dichloromethane were added 0.4 ml TFA. After 12 h stirring at RT the solvents were removed and the residue was codistilled twice with toluene. Yield: 156 mg.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08669266B2 |
| Source dataset | uspto-grants-2014_03 |
| ORD ID | ord-d70357cc525a4bce91a06e0a920a8846 |
| Source note | uspto-grants-2014_03 |