HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ammonia methanol → HCID 71250018, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ammonia methanol | HCID 21705897 | — |
| Reactant | HCID 71245299 | HCID 71245299 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 71250018 | HCID 71250018 | 55% |
Reaction Steps
To a solution of (S)-methyl-2-((S)-1-((S)-1-((S)-2-(benzyloxycarbonylamino)-3-hydroxypropanoyl)-pyrrolidine-2-carbonyl)-pyrrolidine-2-carboxamido)-3-hydroxypropanoate (6) (60 mg, 1.04 mmol) in MeOH was added MeOH—NH3 (3 mL) was stirred at RT for 16 h. The volatiles were evaporated under reduced pressure to afford compound 7 (30 mg, 55%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08673843B2 |
| Source dataset | uspto-grants-2014_03 |
| ORD ID | ord-96f7b3c042e843b7af07a244bed33678 |
| Source note | uspto-grants-2014_03 |