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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1186013Generated: November 1, 2026

Ammonia methanol → HCID 71250018, compound

https://huagongshe.com/reaction/1186013

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAmmonia methanolHCID 21705897—
ReactantHCID 71245299HCID 71245299—
SolventMethanolHCID 887—
ProductHCID 71250018HCID 7125001855%

Reaction Steps

To a solution of (S)-methyl-2-((S)-1-((S)-1-((S)-2-(benzyloxycarbonylamino)-3-hydroxypropanoyl)-pyrrolidine-2-carbonyl)-pyrrolidine-2-carboxamido)-3-hydroxypropanoate (6) (60 mg, 1.04 mmol) in MeOH was added MeOH—NH3 (3 mL) was stirred at RT for 16 h. The volatiles were evaporated under reduced pressure to afford compound 7 (30 mg, 55%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08673843B2
Source datasetuspto-grants-2014_03
ORD IDord-96f7b3c042e843b7af07a244bed33678
Source noteuspto-grants-2014_03