5-(2,2,2-Trifluoroethoxy)pyridine-2-carboxylic acid → HCID 86660410, compound

Participants

Reaction Steps

The title compound was prepared in an analogous manner as described for intermediate B14A from (S)-5-(5-amino-2-fluoro-phenyl)-5,7,7-trimethyl-[1,4]oxazepane-3-thione (intermediate A′7A) (108 mg, 0.38 mmol) and 5-(2,2,2-trifluoro-ethoxy)-pyridine-2-carboxylic acid [CAS No. 881409-53-6; described in intermediate 49] (94 mg, 0.43 mmol). The compound was obtained as a light yellow foam (156 mg, 76%). MS (ISP): m/z=486.3 [(M+H)+].

Provenance & Evidence