Chlorotrimethylsilane → 1-[2-(Chroman-3-yl)ethyl]-4-trimethylsilyloxy-1,2,5,6-tetrahydropyridine
Reaction equation
[CH2:1]([Li:2])[CH2:3][CH2:4][CH3:5].[CH3:37][CH2:38][CH2:39][CH2:40][CH2:41][CH3:42].[CH:6]([NH:7][CH:8]([CH3:9])[CH3:10])([CH3:11])[CH3:12].[Cl:32][Si:33]([CH3:34])([CH3:35])[CH3:36].[O:13]1[CH2:14][CH:15]([CH2:23][CH2:24][N:25]2[CH2:26][CH2:27][C:28](=[O:31])[CH2:29][CH2:30]2)[CH2:16][c:17]2[cH:18][cH:19][cH:20][cH:21][c:22]21.[O:43]1[CH2:44][CH2:45][CH2:46][CH2:47]1>>[O:13]1[CH2:14][CH:15]([CH2:23][CH2:24][N:25]2[CH2:26][CH2:27][C:28]([O:31][Si:33]([CH3:34])([CH3:35])[CH3:36])=[CH:29][CH2:30]2)[CH2:16][c:17]2[cH:18][cH:19][cH:20][cH:21][c:22]21Participants
7
Sources & evidence
- ORD record
- ord-94e380208224408283acaf56df97cea0
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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