Aluminium lithium hydride → HCID 64666716, compound

Participants

Reaction Steps

According to Step 2 of Reference Example 8-63, tetrahydrofuran (10 mL) and a solution prepared by dissolving, in tetrahydrofuran (5 mL), ethyl 2-methyl-3-(pyridin-3-yl)propanoate (200 mg, 1.0 mmol) obtained in Step 2 of Reference Example 8-65 were added to lithium aluminum hydride (75 mg, 2.0 mmol), and the mixture was stirred with cooling in an ice bath for 1 hour. Thus, 2-methyl-3-(pyridin-3-yl)propan-1-ol (Compound EM) (154 mg, yield: 99%) was obtained.

Provenance & Evidence