反应详情

According to Step 3 of Reference Example 8-65, by use of lithium aluminum hydride (75 mg, 2.0 mmol), tetrahydrofuran (10 mL) and a solution prepared by dissolving, in tetrahydrofuran (5 mL), ethyl 3-(pyridin-3-yl)butanoate (339 mg, 2.0 mmol) obtained in Step 2 of Reference Example 8-66, the mixture was stirred and reacted under cooling in an ice bath for 1 hour. Thus, 3-(pyridin-3-yl)butan-1-ol (Compound EN) (153 mg, yield: 99%) was obtained.

1. customa solution prepared
2. customreacted
3. temperatureunder cooling in an ice bath for 1 hour