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HRID 11864作成日:2026年10月25日

(S)-2((4-(N-Cbz)aminomethylbenzoyl)amino)-5-(N-Boc-2-picolylaminomethyl)valeric Acid → (S)-2-((4-aminomethylbenzoyl)amino)-5-(N-Boc-2-picolylaminomethyl)valeric Acid

https://huagongshe.com/reaction/11864

反応式

関与物質

役割名称HCID仕込み量
反応物(S)-2((4-(N-Cbz)aminomethylbenzoyl)amino)-5-(N-Boc-2-picolylaminomethyl)valeric AcidHCID 21043780—
触媒PalladiumHCID 23938—
溶媒MethanolHCID 887—
生成物(S)-2-((4-aminomethylbenzoyl)amino)-5-(N-Boc-2-picolylaminomethyl)valeric AcidHCID 2104375864.3%

反応手順

The compound obtained in Example 41-4 (0.02 g) was dissolved in methanol (0.5 ml). After the addition of 10% Pd—C (0.02 g), the mixture was stirred for 2 hours under hydrogen atmosphere at room temperature. After the reaction, the catalyst was removed by filtration and solvent was removed by distillation. The residue was dried under vacuum to obtain the title compound (0.01 g) as colorless oil.

情報源と証拠

DOI10.6084/m9.figshare.5104873.v1
特許番号US07098215B2
出典データセットuspto-grants-2006_08
ORD IDord-ef91b828fa474015a55771cdc907c24a
出典メモuspto-grants-2006_08