HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Mercaptobenzoic Acid → 2-(4-(Biphenyl-4-ylsulfonamido)-1-hydroxynaphthalen-2-ylthio)benzoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Mercaptobenzoic Acid | HCID 5443 | — |
| Reactant | 2-{[1-Hydroxy-4-(thiophene-2-sulfonamido)naphthalen-2-yl]sulfanyl}acetic acid | HCID 1582605 | — |
| Reactant | (NE)-N-(3-chloro-4-oxonaphthalen-1-ylidene)-4-phenylbenzenesulfonamide | HCID 58398230 | — |
| Product | 2-(4-(Biphenyl-4-ylsulfonamido)-1-hydroxynaphthalen-2-ylthio)benzoic acid | HCID 44609308 | — |
Reaction Steps
5.2.62 2-(4-(biphenyl-4-ylsulfonamido)-1-hydroxynaphthalen-2-ylthio)benzoic acid (14t) was prepared according to the procedure of procedure B for 10a except using 2-thiosalicylic acid and (E)-N-(3-chloro-4-oxonaphthalen-1(4H)-ylidene)biphenyl-4-sulfonamide (12b), which afforded the title compound 17.4 mg (65.9%) as an off-white solid, m.p.: 205° C. (dec.).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08673910B2 |
| Source dataset | uspto-grants-2014_03 |
| ORD ID | ord-44a9883ad1c544baa052de2937dc4d7f |
| Source note | uspto-grants-2014_03 |