Oxalyl chloride → HCID 86690001, compound

HRID 1186730Notes

Reaction equation

HRID 1186730 reaction equation
[NH2:1][C:2]1[C:11]2[CH2:10][CH2:9][CH2:8][CH2:7][C:6]=2[CH:5]=[CH:4][C:3]=1[NH:12][C:13]1[CH:21]=[CH:20][CH:19]=[C:18]2[C:14]=1[CH:15]=[CH:16][N:17]2[CH2:22][O:23][CH2:24][CH2:25][Si:26]([CH3:29])([CH3:28])[CH3:27].[C:30](Cl)(=[O:34])[C:31](Cl)=[O:32]>>[CH3:27][Si:26]([CH3:29])([CH3:28])[CH2:25][CH2:24][O:23][CH2:22][N:17]1[C:18]2[C:14](=[C:13]([N:12]3[C:3]4[CH:4]=[CH:5][C:6]5[CH2:7][CH2:8][CH2:9][CH2:10][C:11]=5[C:2]=4[NH:1][C:31](=[O:32])[C:30]3=[O:34])[CH:21]=[CH:20][CH:19]=2)[CH:15]=[CH:16]1

Participants

3

Reactant 2

HCID 65578Oxalyl chlorideHCID 86690002HCID 86690002, compound

Product 1

HCID 86690001HCID 86690001, compound

Procedure

1-Amino-2-[1-[2-(trimethylsilyl)ethoxymethyl]-1H-indol-4-yl]amino-5,6,7,8-tetrahydronaphthalene and oxalyl chloride were used in a process similar to Example 1(3) to give the titled compound.

Sources & evidence

ORD record
ord-73b20691aa554dc0a8eeb71990b4581c
Source dataset
uspto-grants-2014_03
Patent number
US08673915B2

Reaction notes

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