Oxalyl chloride → HCID 86690007, compound

HRID 1186737Notes

Reaction equation

[NH2:1][C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[CH:5]=[CH:4][C:3]=1[NH:12][C:13]1[CH:18]=[CH:17][CH:16]=[C:15]([NH:19][C:20]([O:22][C:23]([CH3:26])([CH3:25])[CH3:24])=[O:21])[CH:14]=1.[C:27](Cl)(=[O:31])[C:28](Cl)=[O:29]>>[C:23]([O:22][C:20]([NH:19][C:15]1[CH:14]=[C:13]([N:12]2[C:3]3[CH:4]=[CH:5][C:6]4[CH:7]=[CH:8][CH:9]=[CH:10][C:11]=4[C:2]=3[NH:1][C:28](=[O:29])[C:27]2=[O:31])[CH:18]=[CH:17][CH:16]=1)=[O:21])([CH3:26])([CH3:25])[CH3:24]

Participants

Reactant 2

HCID 65578Oxalyl chloride

HCID 86690008HCID 86690008, compound

Product 1

HCID 86690007HCID 86690007, compoundYield 41%

Procedure

1-Amino-2-(3-tertbutoxycarbonylaminophenyl)aminonaphthalene (1.05 g, 3 mmol) and oxalyl chloride were used in a process similar to Example 1(3) to give the titled compound (0.50 g, yield 41%).

Sources & evidence

ORD record: ord-e478f03807af4751ad0d4cd7ac7e0637
Source dataset: uspto-grants-2014_03
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08673915B2

Reaction notes

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