Oxalyl chloride → HCID 56640441, compound

HRID 1186740Notes

Reaction equation

HRID 1186740 reaction equation
[NH2:1][C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[CH:5]=[CH:4][C:3]=1[NH:12][C:13]1[CH:18]=[CH:17][CH:16]=[C:15]([C:19]2[O:20][C:21]([CH3:24])=[N:22][N:23]=2)[CH:14]=1.[C:25](Cl)(=[O:29])[C:26](Cl)=[O:27]>>[CH3:24][C:21]1[O:20][C:19]([C:15]2[CH:14]=[C:13]([N:12]3[C:3]4[CH:4]=[CH:5][C:6]5[CH:7]=[CH:8][CH:9]=[CH:10][C:11]=5[C:2]=4[NH:1][C:26](=[O:27])[C:25]3=[O:29])[CH:18]=[CH:17][CH:16]=2)=[N:23][N:22]=1

Participants

3

Reactant 2

HCID 65578Oxalyl chlorideHCID 86690012HCID 86690012, compound

Product 1

HCID 56640441HCID 56640441, compoundYield 40%

Procedure

1-Amino-2-[3-(5-methyl-[1,3,4]oxadiazol-2-yl)phenyl]aminonaphthalene (95 mg, 0.3 mmol) and oxalyl chloride were used in a process similar to Example 1(3) to give the titled compound as white crystal (43 mg, yield 40%).

Sources & evidence

ORD record
ord-d1c827477d3d43d9b1ede1b4896845ca
Source dataset
uspto-grants-2014_03
Patent number
US08673915B2

Reaction notes

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