Piconol → HCID 58075191, compound

HRID 1186788Notes

Reaction equation

HRID 1186788 reaction equation
[Cl:1][C:2]1[N:3]=[N:4][C:5](Cl)=[CH:6][CH:7]=1.[OH:9][CH2:10][C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][N:12]=1>>[Cl:1][C:2]1[N:3]=[N:4][C:5]([O:9][CH2:10][C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][N:12]=2)=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 11474PiconolHCID 673313,6-Dichloropyridazine

Product 1

HCID 58075191HCID 58075191, compound

Procedure

3,6-Dichloropyridazine (1.0 g, 6.712 mmol) was reacted analogously to example 4a with 2-hydroxymethylpyridine (732 mg, 6.712 mmol). Yield: 1.26 g (85%), M+H+: 222.1.

Sources & evidence

ORD record
ord-68a7eab1078b4ee0b30550213bb3bd37
Source dataset
uspto-grants-2014_03
Patent number
US08673917B2

Reaction notes

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