Ethanol → 8-tert-Butyl-4-(2-hydroxymethyl-3-{1-methyl-5-[5-(morpholine-4-carbonyl)-pyridin-2-ylamino]-6-oxo-1,6-dihydro-pyridin-3-yl}-phenyl)-1,2,3,4-tetrahydro-benzo[e][1,4]diazepin-5-one
Reaction equation
[BH4-:51].[C:1]([CH3:2])([CH3:3])([CH3:4])[c:5]1[cH:6][cH:7][c:8]2[c:9]([cH:47]1)[NH:10][CH2:11][CH2:12][N:13]([c:16]1[c:17]([CH:18]=[O:19])[c:20](-[c:24]3[cH:25][n:26]([CH3:46])[c:27](=[O:45])[c:28]([NH:30][c:31]4[n:32][cH:33][c:34]([C:37](=[O:38])[N:39]5[CH2:40][CH2:41][O:42][CH2:43][CH2:44]5)[cH:35][cH:36]4)[cH:29]3)[cH:21][cH:22][cH:23]1)[C:14]2=[O:15].[CH2:53]1[O:54][CH2:55][CH2:56][CH2:57]1.[CH3:48][CH2:49][OH:50].[Na+:52]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[c:5]1[cH:6][cH:7][c:8]2[c:9]([cH:47]1)[NH:10][CH2:11][CH2:12][N:13]([c:16]1[c:17]([CH2:18][OH:19])[c:20](-[c:24]3[cH:25][n:26]([CH3:46])[c:27](=[O:45])[c:28]([NH:30][c:31]4[n:32][cH:33][c:34]([C:37](=[O:38])[N:39]5[CH2:40][CH2:41][O:42][CH2:43][CH2:44]5)[cH:35][cH:36]4)[cH:29]3)[cH:21][cH:22][cH:23]1)[C:14]2=[O:15]Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-c63b617fd9a84c218d69c9671f8583a4
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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