HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-(2-Piperazin-1-ylethyl)-2,1,3-benzoxadiazole → 5-(2-{4-[2-(2,1,3-benzoxadiazol-5-yl)ethyl]piperazin-1-yl}-1-hydroxyethyl)-2-benzofuran-1(3H)-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-(2-Piperazin-1-ylethyl)-2,1,3-benzoxadiazole | HCID 15166382 | — |
| Reactant | 5-(oxiran-2-yl)-2-benzofuran-1(3H)-one | HCID 59568715 | — |
| Product | 5-(2-{4-[2-(2,1,3-benzoxadiazol-5-yl)ethyl]piperazin-1-yl}-1-hydroxyethyl)-2-benzofuran-1(3H)-one | HCID 49802495 | — |
Reaction Steps
5-(2-{4-[2-(2,1,3-benzoxadiazol-5-yl)ethyl]piperazin-1-yl}-1-hydroxyethyl)-2-benzofuran-1(3H)-one was prepared in a similar fashion as to the synthesis described in EXAMPLE 12 starting from 5-[2-(piperazin-1-yl)ethyl]-2,1,3-benzoxadiazole and 5-oxiran-2-yl-2-benzofuran-1(3H)-one. LC/MS: [(M+1)]+=409.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08673920B2 |
| Source dataset | uspto-grants-2014_03 |
| ORD ID | ord-2d27af843f2b47f3816e96fed95acc79 |
| Source note | uspto-grants-2014_03 |