m-Chloroperbenzoic acid → HCID 86611495, compound

HRID 1187395Notes

Reaction equation

HRID 1187395 reaction equation
[CH2:1]([O:3][CH2:4][C:5]1[N:6]([CH2:18][CH2:19][CH2:20][O:21][N:22]=[C:23]([CH3:25])[CH3:24])[C:7]2[C:16]3[CH:15]=[CH:14][CH:13]=[CH:12][C:11]=3[N:10]=[CH:9][C:8]=2[N:17]=1)[CH3:2].C1C=C(Cl)C=C(C(OO)=[O:34])C=1>>[CH2:1]([O:3][CH2:4][C:5]1[N:6]([CH2:18][CH2:19][CH2:20][O:21][N:22]=[C:23]([CH3:24])[CH3:25])[C:7]2[C:16]3[CH:15]=[CH:14][CH:13]=[CH:12][C:11]=3[N+:10]([O-:34])=[CH:9][C:8]=2[N:17]=1)[CH3:2]

Participants

3

Reactant 2

HCID 70297m-Chloroperbenzoic acidHCID 86611496HCID 86611496, compound

Product 1

HCID 86611495HCID 86611495, compoundYield 65.6%

Procedure

The general method described in Part C of Example 5 was used to oxidize acetone O-{3-[2-(ethoxymethyl)-1H-imidazo[4,5-c]quinolin-1-yl]propyl}oxime (1.06 g, 3.12 mmol) with mCPBA (838 mg, 3.74 mmol) to provide 729 mg of acetone O-{3-[2-(ethoxymethyl)-5-oxido-1H-imidazo[4,5-c]quinolin-1-yl]propyl}oxime as a red solid.

Sources & evidence

ORD record
ord-ced221dcfeab40338937dbee3a2b705c
Source dataset
uspto-grants-2014_03
Patent number
US08673932B2

Reaction notes

Loading…