Phosphorus oxychloride → 5-Chloro-2-(3-fluoropyridin-4-yl)-3-pyridin-3-ylpyrazine
Reaction equation
[F:1][c:2]1[cH:3][n:4][cH:5][cH:6][c:7]1-[c:8]1[n:9][cH:10][c:11](=[O:20])[nH:12][c:13]1-[c:14]1[cH:15][n:16][cH:17][cH:18][cH:19]1.[P:21]([Cl:22])([Cl:23])([Cl:24])=[O:25]>>[F:1][c:2]1[cH:3][n:4][cH:5][cH:6][c:7]1-[c:8]1[n:9][cH:10][c:11]([Cl:23])[n:12][c:13]1-[c:14]1[cH:15][n:16][cH:17][cH:18][cH:19]1Participants
3
Sources & evidence
- ORD record
- ord-02ff974c0c494e688fd2ed02329d3ee3
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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