HuagongsheHuagongshe Chemistry Print Report · For research reference only
N,N-dicyclopropyl-6-ethyl-1-methyl-4-thioureido-1,6-dihydroimidazo[4,5-d]pyrrolo[2,3-b]pyridine-7-carboxamide → N,N-dicyclopropyl-6-ethyl-4-(4-(isopropylsulfonylmethyl)thiazol-2-ylamino)-1-methyl-1,6-dihydroimidazo[4,5-d]pyrrolo[2,3-b]pyridine-7-carboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N,N-dicyclopropyl-6-ethyl-1-methyl-4-thioureido-1,6-dihydroimidazo[4,5-d]pyrrolo[2,3-b]pyridine-7-carboxamide | HCID 58180527 | — |
| Reactant | 1-Chloro-1-(isopropylsulfonyl)propan-2-one | HCID 58180635 | — |
| Product | N,N-dicyclopropyl-6-ethyl-4-(4-(isopropylsulfonylmethyl)thiazol-2-ylamino)-1-methyl-1,6-dihydroimidazo[4,5-d]pyrrolo[2,3-b]pyridine-7-carboxamide | HCID 58180569 | — |
Reaction Steps
Prepared from N,N-dicyclopropyl-6-ethyl-1-methyl-4-thioureido-1,6-dihydroimidazo[4,5-d]pyrrolo[2,3-b]pyridine-7-carboxamide (example 2B) and 1-chloro-1-(isopropylsulfonyl)propan-2-one (example 5a) using same procedure as reported for 2.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08673933B2 |
| Source dataset | uspto-grants-2014_03 |
| ORD ID | ord-f7a8ee4b92c84350a073637178b56cde |
| Source note | uspto-grants-2014_03 |