HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 86643472, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Ethyl Acetate | HCID 8857 | — |
| Reactant | HCID 25001105 | HCID 25001105 | — |
| Product | HCID 86643472 | HCID 86643472 | 25% |
Reaction Steps
N-Benzyl-5-((5-(4-fluorophenyl)-1H-pyrazol-3-ylamino)methyl)thiazol-2-amine (59 mg, 0.13 mmol) was dissolved in methanolic HCl (3 N, 1 mL) and AcOEt was added. The precipitated solid was filtered by decantation and dried in vacuo, yielding N-benzyl-5-((5-(4-fluorophenyl)-1H-pyrazol-3-ylamino)methyl)thiazol-2-amine dihydrochloride as a yellow solid (14 mg, 25%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08673940B2 |
| Source dataset | uspto-grants-2014_03 |
| ORD ID | ord-4efea87b4bac45138a582a51a855ef42 |
| Source note | uspto-grants-2014_03 |