HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 59408770, compound → HCID 59408767, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 59408770 | HCID 59408770 | — |
| Solvent | Propylamine | HCID 7852 | — |
| Product | HCID 59408767 | HCID 59408767 | 124.4% |
Reaction Steps
A solution of 6-bromo-N-(5-bromopyridin-2-yl)nicotinamide 3 (1.1 g, 3.0 mmol) in n-propylamine (neat, 5 ml) was heated at 80° C. for 2 days. Then the solvent was evaporated to give 6-(propylamino)-N-(5-(propylamino)pyridin-2-yl)nicotinamide 4 as a white solid (880 mg, 91%). Mp. 134-135° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08673940B2 |
| Source dataset | uspto-grants-2014_03 |
| ORD ID | ord-ea7902b3b11546d7b262de4990618004 |
| Source note | uspto-grants-2014_03 |