Hydrochloric Acid → HCID 178423773, compound

HRID 1188148Notes

Reaction equation

HRID 1188148 reaction equation
[C:1]1([CH3:33])[CH:6]=[CH:5][C:4]([C:7]2[NH:11][N:10]=[C:9]([NH:12][CH2:13][C:14]3[CH:18]=[C:17]([NH:19][CH2:20][C:21]4[CH:25]=[C:24]([C:26]5[CH:31]=[CH:30][C:29]([CH3:32])=[CH:28][CH:27]=5)[NH:23][N:22]=4)[NH:16][N:15]=3)[CH:8]=2)=[CH:3][CH:2]=1.[ClH:34]>>[ClH:34].[ClH:34].[ClH:34].[C:1]1([CH3:33])[CH:2]=[CH:3][C:4]([C:7]2[NH:11][N:10]=[C:9]([NH:12][CH2:13][C:14]3[CH:18]=[C:17]([NH:19][CH2:20][C:21]4[CH:25]=[C:24]([C:26]5[CH:31]=[CH:30][C:29]([CH3:32])=[CH:28][CH:27]=5)[NH:23][N:22]=4)[NH:16][N:15]=3)[CH:8]=2)=[CH:5][CH:6]=1

Participants

3

Reactant 2

HCID 313Hydrochloric AcidHCID 178423772HCID 178423772, compound

Product 1

HCID 178423773HCID 178423773, compound

Procedure

5-p-Tolyl-N-((5-((5-p-tolyl-1H-pyrazol-3-yl)methylamino)-1H-pyrazol-3-yl)methyl)-1H-pyrazol-3-amine (10 mg, 0.023 mmol) was recrystallized in methanolic HCl (3 N, 0.5 mL). The solid was filtered, washed with Et2O and dried in vacuo to give a white solid. Mp.=167° C.

Workup

  1. filtrationThe solid was filtered
  2. washwashed with Et2O
  3. customdried in vacuo
  4. customto give a white solid

Sources & evidence

ORD record
ord-1d5aef7a31c543c99e6eccf0e0a6e8d6
Source dataset
uspto-grants-2014_03
Patent number
US08673940B2

Reaction notes

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