Dichloromethane → Methyl 3-amino-2,3-dihydro-1H-indene-5-carboxylate

HRID 118850Notes

Reaction equation

HRID 118850 reaction equation
[C:8]([O:9][C:10](=[O:11])[NH:15][CH:16]1[CH2:17][CH2:18][c:19]2[cH:20][cH:21][c:22]([C:25](=[O:26])[O:27][CH3:28])[cH:23][c:24]21)([CH3:12])([CH3:13])[CH3:14].[CH2:29]([Cl:30])[Cl:31].[F:1][C:2]([F:3])([F:4])[C:5]([OH:6])=[O:7]>>[NH2:15][CH:16]1[CH2:17][CH2:18][c:19]2[cH:20][cH:21][c:22]([C:25](=[O:26])[O:27][CH3:28])[cH:23][c:24]21

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 59505261methyl (3R)-3-(tert-butoxycarbonylamino)indane-5-carboxylate

Product 1

HCID 58686623Methyl 3-amino-2,3-dihydro-1H-indene-5-carboxylate

Sources & evidence

ORD record
ord-20505c1a04b246508c171fdb908ac318
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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