Acetate → N-(3-Fluoro-4-((6-methoxy-7-(3-morpholinopropoxy)quinolin-4-yl)-oxy)phenyl)-N-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide

HRID 118851노트

반응식

[Cl:1][c:2]1[cH:3][cH:4][n:5][c:6]2[cH:7][c:8]([O:14][CH2:15][CH2:16][CH2:17][N:18]3[CH2:19][CH2:20][O:21][CH2:22][CH2:23]3)[c:9]([O:12][CH3:13])[cH:10][c:11]12.[F:24][c:25]1[cH:26][c:27]([N:32]([C:33](=[O:34])[C:35]2([C:38](=[O:39])[NH2:40])[CH2:36][CH2:37]2)[c:41]2[cH:42][cH:43][c:44]([F:47])[cH:45][cH:46]2)[cH:28][cH:29][c:30]1[OH:31].[K+:53].[K+:54].[K+:55].[O-:57][C:58]([CH3:59])=[O:60].[O-:61][C:62]([CH3:63])=[O:64].[P:48]([O-:49])([O-:50])([O-:51])=[O:52].[Pd+2:56]>>[c:2]1([O:31][c:30]2[c:25]([F:24])[cH:26][c:27]([N:32]([C:33](=[O:34])[C:35]3([C:38](=[O:39])[NH2:40])[CH2:36][CH2:37]3)[c:41]3[cH:42][cH:43][c:44]([F:47])[cH:45][cH:46]3)[cH:28][cH:29]2)[cH:3][cH:4][n:5][c:6]2[cH:7][c:8]([O:14][CH2:15][CH2:16][CH2:17][N:18]3[CH2:19][CH2:20][O:21][CH2:22][CH2:23]3)[c:9]([O:12][CH3:13])[cH:10][c:11]12