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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1188512Generated: October 25, 2026

2,2,2-Trifluoroethyl trifluoromethanesulfonate → 4-Chloro-5-(methyloxy)-1-(2,2,2-trifluoroethyl)-2-(trifluoromethyl)-1H-benzimidazole

https://huagongshe.com/reaction/1188512

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,2,2-Trifluoroethyl trifluoromethanesulfonateHCID 80366—
Reactant4-Chloro-5-(methyloxy)-2-(trifluoromethyl)-1H-benzimidazoleHCID 57800294—
Product4-Chloro-5-(methyloxy)-1-(2,2,2-trifluoroethyl)-2-(trifluoromethyl)-1H-benzimidazoleHCID 57800146—

Reaction Steps

Synthesized as described in Example 195D from 4-chloro-5-(methyloxy)-2-(trifluoromethyl)-1H-benzimidazole and trifluoroethyl triflate: MS (ESI) m/z 333 (M+1).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08673948B2
Source datasetuspto-grants-2014_03
ORD IDord-3e7b1a7380ea4952b5c3c13b04217e49
Source noteuspto-grants-2014_03