HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Chloro-2-fluorobenzoic acid → 1-{[5-(5-Chloro-2-fluorophenyl)-1,2,4-oxadiazol-3-yl]methyl}-4-(trifluoromethyl)-1H-indole-5-carbonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Chloro-2-fluorobenzoic acid | HCID 2736537 | — |
| Reactant | HCID 178509476 | HCID 178509476 | — |
| Product | 1-{[5-(5-Chloro-2-fluorophenyl)-1,2,4-oxadiazol-3-yl]methyl}-4-(trifluoromethyl)-1H-indole-5-carbonitrile | HCID 57800212 | — |
Reaction Steps
Synthesized as described in Example 241 from 2-[5-cyano-4-(trifluoromethyl)-1H-indol-1-yl]-N-hydroxyethanimidamide and 5-chloro-2-fluorobenzoic acid: MS (APCI) m/z 421 (M+1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08673948B2 |
| Source dataset | uspto-grants-2014_03 |
| ORD ID | ord-3a92053c073b4b41b3dab1f418cd4b32 |
| Source note | uspto-grants-2014_03 |