Hydrochloric Acid → 3-Amino-4-chloro-2-fluorobenzoic acid

HRID 1189620Notes

Reaction equation

C([NH:4][C:5]1[C:6]([F:15])=[C:7]([CH:11]=[CH:12][C:13]=1[Cl:14])[C:8]([OH:10])=[O:9])(=O)C.Cl>>[NH2:4][C:5]1[C:6]([F:15])=[C:7]([CH:11]=[CH:12][C:13]=1[Cl:14])[C:8]([OH:10])=[O:9]

Participants

Reactant 2

HCID 313Hydrochloric Acid

HCID 667650633-Acetylamino-4-chloro-2-fluoro-benzoic acid

Product 1

HCID 667650743-Amino-4-chloro-2-fluorobenzoic acidYield 96%

Procedure

The sub-title compound is prepared from 3-acetylamino-4-chloro-2-fluoro-benzoic acid and 6 M HCl-solution in analogy to step Ab.

Sources & evidence

ORD record: ord-ddda73a9ffbd486eaca73dfa2b1bde13
Source dataset: uspto-grants-2014_03
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08674113B2

Reaction notes

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