反应详情

A mixture of N-(trans-4-trifluoromethyl-cyclohexyl)-2-[3-trifluoromethyl-pyrrolidinyl]-4-methylamino-5-nitro-benzoic acid amide (110 mg, 0.23 mmol), Pd/C (10 mg), THF (5 mL) and MeOH (10 mL) is stirred under 3 bar H2-atmosphere for 2 d. The mixture is filtered, and the filtrate is concentrated and directly used in the next step.

1. filtrationThe mixture is filtered
2. concentrationthe filtrate is concentrated