HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 178482236, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Diisopropylethylamine | HCID 81531 | — |
| Reactant | 3,3-Difluoropyrrolidine | HCID 2782827 | — |
| Reactant | HCID 178482185 | HCID 178482185 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | HCID 178482236 | HCID 178482236 | — |
Reaction Steps
The sub-title compound is prepared in analogy to procedure 6a from N-(trans-4-trifluoromethyl-cyclohexyl)-2-chloro-4-methylamino-5-nitro-benzoic acid amide (190 mg, 0.50 mmol), 3,3-difluoro-pyrrolidine×HCl (143 mg, 1.00 mmol), DIPEA (0.34 mL, 2.0 mmol) and dioxane (10 mL).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08674113B2 |
| Source dataset | uspto-grants-2014_03 |
| ORD ID | ord-3c556be93e294845afa9f33d3eab9c29 |
| Source note | uspto-grants-2014_03 |