HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl-2-[4-trifluoromethyl-piperidinyl]-4-methylamino-5-nitro-benzoate → HCID 67956899, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl-2-[4-trifluoromethyl-piperidinyl]-4-methylamino-5-nitro-benzoate | HCID 67957612 | — |
| Catalyst | Nickel | HCID 935 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 67956899 | HCID 67956899 | — |
Reaction Steps
A mixture of ethyl-2-[4-trifluoromethyl-piperidinyl]-4-methylamino-5-nitro-benzoate (380 mg, 1.01 mmol), Ra—Ni (500 mg) and THF (20 mL) is stirred overnight under 10 bar H2-atmosphere. The mixture is filtered, and the filtrate is concentrated.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08674113B2 |
| Source dataset | uspto-grants-2014_03 |
| ORD ID | ord-4d0e7f2c602243429fbfb5fb8f03c6b1 |
| Source note | uspto-grants-2014_03 |