HRID1189679

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：CNc1c([N+](=O)[O-])cc(C(=O)N[C@H]2CC[C@H](C(F)(F)F)CC2)c(N2CC3CC3C2)c1C

HCID178482285

未命名化合物

PRODUCTS

生成物

结构：CNc1c(N)cc(C(=O)N[C@H]2CC[C@H](C(F)(F)F)CC2)c(N2CC3CC3C2)c1C

HCID178482278

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

催化剂HCID23938

Palladium

溶剂HCID887

Methanol

CH4O

PROCEDURE

实验过程

The sub-title compound is prepared in analogy to 6b from N-(trans-4-trifluoromethyl-cyclohexyl)-2-[3-aza-bicyclo[3.1.0]hex-3-yl]-3-methyl-4-methylamino-5-nitro-benzoic acid amide (130 mg, 0.295 mmol), Pd/C (50 mg), MeOH (40 mL) and 3 bar H2-atmosphere. Yield: 85 mg. HPLC Rt=1.31 min (method A). MS m/z: 411 [M+H]+.