HCID 178482285, compound → HCID 178482278, compound

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Reaction Steps

The sub-title compound is prepared in analogy to 6b from N-(trans-4-trifluoromethyl-cyclohexyl)-2-[3-aza-bicyclo[3.1.0]hex-3-yl]-3-methyl-4-methylamino-5-nitro-benzoic acid amide (130 mg, 0.295 mmol), Pd/C (50 mg), MeOH (40 mL) and 3 bar H2-atmosphere. Yield: 85 mg. HPLC Rt=1.31 min (method A). MS m/z: 411 [M+H]+.

Provenance & Evidence