HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 67957189, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Diisopropylethylamine | HCID 81531 | — |
| Reactant | 4-(Trifluoromethyl)piperidine | HCID 136469 | — |
| Reactant | Methyl 2-chloro-4-(methylamino)-5-nitrobenzoate | HCID 67957559 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | HCID 67957189 | HCID 67957189 | — |
Reaction Steps
The sub-title compound is prepared in analogy to 26a from methyl-2-chloro-4-methylamino-5-nitro-benzoate (1.37 g, 5.6 mmol), 4-trifluoromethylpiperidine×HCl (1.27 g, 6.7 mmol), DIPEA (3.8 mL, 22 mmol) and dioxane (50 mL).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08674113B2 |
| Source dataset | uspto-grants-2014_03 |
| ORD ID | ord-2ab3acc197904a6a960bc18143170a8f |
| Source note | uspto-grants-2014_03 |