HuagongsheHuagongshe Chemistry Print Report · For research reference only
Diisopropylcarbodiimide → HCID 86666491, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Diisopropylcarbodiimide | HCID 12734 | — |
| Reactant | (2,4-Dichloro-3-isothiocyanato-benzyl)-carbamic acid tert-butyl ester | HCID 56840196 | — |
| Reactant | HCID 86666490 | HCID 86666490 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 86666491 | HCID 86666491 | — |
Reaction Steps
The title compound is prepared in analogy to 1e from N-(3,3,3-trifluoro-propyl)-2-[4-trifluoromethyl-piperidinyl]-4-methylamino-5-amino-benzoic acid amide (2.3 g, 5.6 mmol), (2,4-dichloro-3-isothiocyanato-benzyl)-carbamic acid tert.-butyl ester (compound B; 1.85 g, 5.6 mmol), DIC (1.0 mL) and DMF (10 mL).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08674113B2 |
| Source dataset | uspto-grants-2014_03 |
| ORD ID | ord-cd06fe3f4f2b449aaa3d3aa04c5e0386 |
| Source note | uspto-grants-2014_03 |