3-Hydroxy-2-naphthoic acid → HCID 68212688, compound
Reaction equation
[OH:1][C:2]1[C:3]([C:12](O)=O)=[CH:4][C:5]2[C:10]([CH:11]=1)=[CH:9][CH:8]=[CH:7][CH:6]=2.[Cl:15][C:16]1[CH:21]=[CH:20][C:19](Br)=[CH:18][CH:17]=1.Br[C:24]1C=CC=CC=1>>[Cl:15][C:16]1[CH:21]=[CH:20][C:19]([CH2:12][C:3]2[C:2]([O:1][CH3:24])=[CH:11][C:10]3[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=3)[CH:4]=2)=[CH:18][CH:17]=1Participants
4
Procedure
Using 3-hydroxy-2-naphthoic acid as the starting material, and 4-chlorobromobenzene to replace bromobenzene, the procedures of Examples 3-7 were repeated to obtain the compound 2-(4-chlorobenzyl)-3-methoxynaphthalene.
Sources & evidence
- ORD record
- ord-04ab1d5a2d644992a3915fc94f3205a4
- Source dataset
- uspto-grants-2014_03
- Patent number
- US08674136B2
Reaction notes
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