p-Bromochlorobenzene → 1,6-Dibromo-2methoxy-3-benzylnaphthalene

HRID 1189714Notes

Reaction equation

HRID 1189714 reaction equation
[Br:1][C:2]1[C:11]2[C:6](=[CH:7][C:8]([Br:12])=[CH:9][CH:10]=2)[CH:5]=[C:4]([C:13](O)=O)[C:3]=1[OH:16].Cl[C:18]1[CH:23]=[CH:22][C:21](Br)=[CH:20][CH:19]=1.Br[C:26]1[CH:31]=[CH:30][CH:29]=[CH:28][CH:27]=1>>[Br:1][C:2]1[C:11]2[C:6](=[CH:7][C:8]([Br:12])=[CH:9][CH:10]=2)[CH:5]=[C:4]([CH2:13][C:18]2[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=2)[C:3]=1[O:16][CH3:26].[Br:1][C:2]1[C:11]2[C:6](=[CH:7][C:8]([Br:12])=[CH:9][CH:10]=2)[CH:5]=[C:4]([CH2:13][C:26]2[CH:31]=[CH:30][CH:29]=[CH:28][CH:27]=2)[C:3]=1[OH:16]

Participants

5

Reactant 3

HCID 7806p-BromochlorobenzeneHCID 7961BromobenzeneHCID 745022-Naphthalenecarboxylic acid, 4,7-dibromo-3-hydroxy-

Product 2

HCID 682124001,6-Dibromo-2methoxy-3-benzylnaphthaleneHCID 682124031,6-Dibromo-3-benzyl-2-naphthol

Procedure

Using the Example 1 compound 4,7-dibromo-3-hydroxy-2-naphthoic acid as the starting material, and 4-chlorobromobenzene to replace bromobenzene, the procedures of Examples 3-7 were repeated to obtain compounds 1,6-dibromo-2methoxy-3-benzylnaphthalene and 1,6-dibromo-3-benzyl-2-naphthol.

Sources & evidence

ORD record
ord-5bc5b3ba38e643eaa52f38586d9cd346
Source dataset
uspto-grants-2014_03
Patent number
US08674136B2

Reaction notes

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