HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoroacetic acid → HCID 70975458, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | HCID 86673546 | HCID 86673546 | — |
| Product | HCID 70975458 | HCID 70975458 | 77.4% |
Reaction Steps
The specific operation referred to the step (6) described in Example 1. 264 mg (R)-1-[1-(2,5-difluorobenzyl)-3-methyl-2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-7-yl]piperidin-3-yl carbamic acid ter.-butyl ester (0.558 mmol) and 3.83 mL trifluoroacetic acid were charged to afford 161 mg titled product with a yield of 77.4%.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08680089B2 |
| Source dataset | uspto-grants-2014_03 |
| ORD ID | ord-9c95aca83eff4ff19b2d20314decc1cb |
| Source note | uspto-grants-2014_03 |