HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoroacetic acid → HCID 70975387, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | HCID 86673547 | HCID 86673547 | — |
| Product | HCID 70975387 | HCID 70975387 | 60.2% |
Reaction Steps
The specific operation referred to the step (6) described in Example 1 for details. 161 mg (R)-1-[1-(2-chlorobenzyl)-3-methyl-2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-7-yl]piperidin-3-yl carbamic acid ter.-butyl ester (0.342 mmol) and 2.4 mL trifluoroacetic acid were charged to afford 100 mg titled product with a yield of 60.2%.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08680089B2 |
| Source dataset | uspto-grants-2014_03 |
| ORD ID | ord-c51665bcc4fb499ab8cf497884613564 |
| Source note | uspto-grants-2014_03 |