Hydrochloric Acid → HCID 19799804, compound

HRID 1190906Notes

Reaction equation

HRID 1190906 reaction equation
[OH:1][C:2]1[CH:3]=[C:4]([NH:14]C(=O)C)[CH:5]=[CH:6][C:7]=1[CH2:8][N:9]1[CH2:13][CH2:12][CH2:11][CH2:10]1.Cl>>[NH2:14][C:4]1[CH:5]=[CH:6][C:7]([CH2:8][N:9]2[CH2:13][CH2:12][CH2:11][CH2:10]2)=[C:2]([OH:1])[CH:3]=1

Participants

3

Reactant 2

HCID 313Hydrochloric AcidHCID 11322268HCID 11322268, compound

Product 1

HCID 19799804HCID 19799804, compound

Procedure

N-[3-hydroxy-4-(pyrrolidin-1-ylmethyl)phenyl]acetamide (0.14 g, 0.61 mmol), hydrochloric acid 20% (1 mL). The mixture was refluxed 6 h, evaporated and used for the next step.

Workup

  1. temperatureThe mixture was refluxed 6 h
  2. customevaporated

Sources & evidence

ORD record
ord-3884731ecce14ed09c9eba65bfd69c6a
Source dataset
uspto-grants-2014_03
Patent number
US08680095B2

Reaction notes

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