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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 11912Generated: October 27, 2026

(R)-6-chloro-4-methyl-3,4-dihydro-2H-2,4a,5-triaza-fluoren-1-one → (R)-6-Bromo-4-methyl-3,4-dihydro-2H-2,4a,5-triaza-fluoren-1-one

https://huagongshe.com/reaction/11912

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(R)-6-chloro-4-methyl-3,4-dihydro-2H-2,4a,5-triaza-fluoren-1-oneHCID 86590110—
Reactant(R)-6-Bromo-1-(2-tert-butoxycarbonylamino-1-methyl-ethyl)-1H-pyrrolo[2,3-b]pyridine-2-carboxylic acid ethyl esterHCID 86596358—
Product(R)-6-Bromo-4-methyl-3,4-dihydro-2H-2,4a,5-triaza-fluoren-1-oneHCID 86760226—

Reaction Steps

This compound was prepared in analogy to Example 1, intermediate b) from (R)-6-bromo-1-(2-tert-butoxycarbonylamino-1-methyl-ethyl)-1H-pyrrolo[2,3-b]pyridine-2-carboxylic acid ethyl ester.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07098337B2
Source datasetuspto-grants-2006_08
ORD IDord-e07af560f18e4cd3afc3bb14e37b2cbe
Source noteuspto-grants-2006_08