1,4-Dioxaspiro[4.5]decan-8-one → HCID 86634389, compound

Participants

Reaction Steps

The same procedure as a series of reactions of Example 9 was carried out, except that 4-azepan-1-yl-N-[(2R,3S)-2-(3-azidopropyl)pyrrolidin-3-yl]-6-chloropyrimidin-2-amine was used in place of the compound 8 and 1,4-dioxaspiro[4.5]decan-8-one was used in place of cyclohexanone in the process of Example 9, to obtain the title compound (1.25 g) having the following physical properties.

Provenance & Evidence