Hydrochloric Acid → HCID 86696996, compound

Participants

Reaction Steps

To a 0° C. solution of compound 47 (1.0 g, 3.0 mmol) in DCM (15 mL) was added 4 N HCl in dioxane (3.8 mL, 15 mmol). Allowed to stir at room temperature for 3 hours, then concentrated under vacuum to give compound 109 (810 mg, quantitative) as a white solid.

Provenance & Evidence