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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1191475Generated: November 1, 2026

Sodium Iodide → HCID 68908687, compound

https://huagongshe.com/reaction/1191475

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSodium IodideHCID 5238—
ReactantDimethylformamideHCID 6228—
ReactantPotassium CarbonateHCID 11430—
Reactant3-Butyl-8-azabicyclo[3,2,1]octaneHCID 68907966—
ProductHCID 68908687HCID 68908687—

Reaction Steps

Crude (R,S)-1-(3-chloro-2-methylpropyl)-3,4-dihydro-1H-quinolin-2-one (107LH63) (0.094 g), 3-butyl-8-azabicyclo[3.2.1]octane (0.025 g, 0.15 mmol), NaI (0.100 g, 0.67 mmol), and K2CO3 (0.075 g, 0.54 mmol) in DMF (1 mL) were reacted and purified according to GP20 to give the title compound (107LH74-c4) (0.025 g). HPLC-MS (ammonium acetate) [M+H]+=369.33.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08680115B2
Source datasetuspto-grants-2014_03
ORD IDord-0adcdd49d19643bebc6ba7134a109da7
Source noteuspto-grants-2014_03