Dimethylmaleic anhydride → HCID 3623055, compound

HRID 1191696Notes

Reaction equation

HRID 1191696 reaction equation
[CH3:1][C:2]1[C:3]([O:5][C:6](=[O:9])[C:7]=1[CH3:8])=O.[CH3:10][O:11][C:12]1[CH:19]=[CH:18][C:15]([CH2:16][NH2:17])=[CH:14][CH:13]=1>C(O)(=O)C>[CH3:10][O:11][C:12]1[CH:19]=[CH:18][C:15]([CH2:16][N:17]2[C:6](=[O:9])[C:7]([CH3:8])=[C:2]([CH3:1])[C:3]2=[O:5])=[CH:14][CH:13]=1

Participants

4

Reactant 2

HCID 13010Dimethylmaleic anhydrideHCID 754524-Methoxybenzylamine

Product 1

HCID 3623055HCID 3623055, compound

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

2,3-Dimethylmaleic anhydride (1 g, 7.9 mmol) and 4-methoxybenzylamine (1 mL, 7.9 mmol) were heated to reflux in 5 mL glacial acetic acid for 4.5 h. Solvent was evaporated. The residue was taken up in EtOAc and washed with sat'd aq NaHCO3, water, and brine. The organic phase was dried (MgSO4), filtered, and evaporated. The title compound was obtained as a solid and used without further purification (1.9 g, quant).

Workup

  1. customSolvent was evaporated
  2. washwashed with sat'd aq NaHCO3, water, and brine
  3. dry with materialThe organic phase was dried (MgSO4)
  4. filtrationfiltered
  5. customevaporated

Sources & evidence

ORD record
ord-29a563035d904a83a136a6cc189ff71b
Source dataset
uspto-grants-2014_03
Patent number
US08680122B2

Reaction notes

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