4-Bromothiophenol → HCID 46932052, compound

HRID 1192036Notes

Reaction equation

HRID 1192036 reaction equation
[Br:1][C:2]1[CH:7]=[CH:6][C:5]([SH:8])=[CH:4][CH:3]=1.Cl[C:10]1[S:14][C:13]([C:15](=[O:17])[CH3:16])=[CH:12][C:11]=1[N+:18]([O-:20])=[O:19]>>[Br:1][C:2]1[CH:7]=[CH:6][C:5]([S:8][C:10]2[S:14][C:13]([C:15](=[O:17])[CH3:16])=[CH:12][C:11]=2[N+:18]([O-:20])=[O:19])=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 660494-BromothiophenolHCID 5211051-(5-Chloro-4-nitrothiophen-2-yl)ethan-1-one

Product 1

HCID 46932052HCID 46932052, compound

Procedure

Prepared according to the procedure described as in Step B for example 1 from 4-Bromobenzenethiol (1.03 g, 5.5 mmol) and 1-(5-chloro-4-nitro-2-thienyl)ethanone (1.14 g, 5.5 mmol). The title compound was obtained as an orange solid (1.15 g, 58% yield). 1H NMR (300 MHz, CDCl3) δ: 8.07 (1H, s) 7.68 (2H, d, J=8.69 Hz), 7.53 (2H, d, J=8.69 Hz), 2.49 (3H, s).

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-f2f5b43a9c2944439765cd6a3e079bcb
Source dataset
uspto-grants-2014_03
Patent number
US08680139B2

Reaction notes

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