Dimethylamine → HCID 46932240, compound

HRID 1192057Notes

Reaction equation

Br[CH:2]([C:4]1[S:8][C:7]([S:9][C:10]2[CH:15]=[CH:14][C:13]([Cl:16])=[CH:12][C:11]=2[Cl:17])=[C:6]([N+:18]([O-:20])=[O:19])[CH:5]=1)[CH3:3].[CH3:21][NH:22][CH3:23]>>[Cl:17][C:11]1[CH:12]=[C:13]([Cl:16])[CH:14]=[CH:15][C:10]=1[S:9][C:7]1[S:8][C:4]([CH:2]([N:22]([CH3:23])[CH3:21])[CH3:3])=[CH:5][C:6]=1[N+:18]([O-:20])=[O:19]

Participants

Reactant 2

HCID 674Dimethylamine

HCID 60207313HCID 60207313, compound

Product 1

HCID 46932240HCID 46932240, compound

Procedure

Prepared according to the procedure described for example 28 from 5-(1-bromoethyl)-2-(2,4-dichlorophenyl)sulfanyl-3-nitro-thiophene (0.1 g, 0.25 mmol) and dimethylamine (0.19 mL, 0.8 mmol). The title compound was obtained as a solid (15 mg, 16% yield). 1H NMR (400 MHz, MeOD) δ: 7.92 (1H, m), 7.88 (1H, m), 7.85 (1H, m) 7.58 (1H, m), 4.74 (1H, q), 2.81 (3H, m), 2.78 (3H, m), 1.67 (3H, d). MS m/z: 376.9 [M+H]+.

Workup

customPrepared

Sources & evidence

ORD record: ord-c42a8c0b0f594346a6bc6327eeeeb82d
Source dataset: uspto-grants-2014_03
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08680139B2

Reaction notes

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