2-Amino-4-methylthiazole → HCID 60207328, compound

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Prepared according to the procedure described for example 70 from 5-[(3,5-dichloro-4-pyridyl)sulfanyl]-4-nitro-thiophene-2-carboxylic acid (200 mg, 0.57 mmol) and 4-methyl-thiazol-2-amine (78 mg, 0.68 mmol). The title compound was obtained as a yellow solid (65 mg, 26% yield). 1H NMR (400 MHz, d6-DMSO) δ: 9.01 (2H, m), 7.24 (1H, m), 6.88 (1H, m), 2.23 (3H, m). MS m/z: 446.92, 448.97 [M+H]+.

Provenance & Evidence