4-[2-(Dimethylamino)ethoxy]aniline → HCID 60207416, compound

HRID 1192199Notes

Reaction equation

HRID 1192199 reaction equation
[Cl:1][C:2]1[CH:3]=[N:4][CH:5]=[C:6]([Cl:20])[C:7]=1[S:8][C:9]1[S:13][C:12]([C:14]([OH:16])=O)=[CH:11][C:10]=1[N+:17]([O-:19])=[O:18].[CH3:21][N:22]([CH3:33])[CH2:23][CH2:24][O:25][C:26]1[CH:32]=[CH:31][C:29]([NH2:30])=[CH:28][CH:27]=1>>[Cl:20][C:6]1[CH:5]=[N:4][CH:3]=[C:2]([Cl:1])[C:7]=1[S:8][C:9]1[S:13][C:12]([C:14]([NH:30][C:29]2[CH:28]=[CH:27][C:26]([O:25][CH2:24][CH2:23][N:22]([CH3:33])[CH3:21])=[CH:32][CH:31]=2)=[O:16])=[CH:11][C:10]=1[N+:17]([O-:19])=[O:18]

Participants

3

Reactant 2

HCID 64846554-[2-(Dimethylamino)ethoxy]anilineHCID 602073175-((3,5-Dichloropyridin-4-yl)thio)-4-nitrothiophene-2-carboxylic acid

Product 1

HCID 60207416HCID 60207416, compound

Procedure

Prepared according to the procedure described for example 44 from 5-[(3,5-dichloro-4-pyridyl)sulfanyl]-4-nitro-thiophene-2-carboxylic acid (35 mg, 0.1 mmol) and 4-(2-(dimethylamino)ethoxy)aniline (17.0 mg, 0.12 mmol). The title compound was obtained as a solid (17.5 mg, 34% yield). MS m/z: 513.02, 515.02 [M+H]+.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-51b0bcec4e4a4eb3a0c0a0c58d9d6949
Source dataset
uspto-grants-2014_03
Patent number
US08680139B2

Reaction notes

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