N~3~,N~3~-Dimethyl-1-phenylpropane-1,3-diamine → HCID 60207426, compound

HRID 1192206Notes

Reaction equation

HRID 1192206 reaction equation
[Cl:1][C:2]1[CH:3]=[N:4][CH:5]=[C:6]([Cl:20])[C:7]=1[S:8][C:9]1[S:13][C:12]([C:14]([OH:16])=O)=[CH:11][C:10]=1[N+:17]([O-:19])=[O:18].[CH3:21][N:22]([CH3:33])[CH2:23][CH2:24][CH:25]([C:27]1[CH:32]=[CH:31][CH:30]=[CH:29][CH:28]=1)[NH2:26]>>[Cl:20][C:6]1[CH:5]=[N:4][CH:3]=[C:2]([Cl:1])[C:7]=1[S:8][C:9]1[S:13][C:12]([C:14]([NH:26][CH:25]([C:27]2[CH:28]=[CH:29][CH:30]=[CH:31][CH:32]=2)[CH2:24][CH2:23][N:22]([CH3:33])[CH3:21])=[O:16])=[CH:11][C:10]=1[N+:17]([O-:19])=[O:18]

Participants

3

Reactant 2

HCID 25248080N~3~,N~3~-Dimethyl-1-phenylpropane-1,3-diamineHCID 602073175-((3,5-Dichloropyridin-4-yl)thio)-4-nitrothiophene-2-carboxylic acid

Product 1

HCID 60207426HCID 60207426, compound

Procedure

Prepared according to the procedure described for example 44 from 5-[(3,5-dichloro-4-pyridyl)sulfanyl]-4-nitro-thiophene-2-carboxylic acid (35 mg, 0.1 mmol) and N1,N1-dimethyl-3-phenylpropane-1,3-diamine (17.8 mg, 0.1 mmol). The title compound was obtained as a solid (15.8 mg, 31% yield). MS m/z: 510.89, 513.89 [M+H]+.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-572cadbb8d1d47ddb70cb62dae010d05
Source dataset
uspto-grants-2014_03
Patent number
US08680139B2

Reaction notes

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