HuagongsheHuagongshe Chemistry Print Report · For research reference only
2,4-Dichloropyrimidine → HCID 43654761, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2,4-Dichloropyrimidine | HCID 77531 | — |
| Reactant | 4-(Trifluoromethoxy)phenylboronic acid | HCID 2734386 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Product | HCID 43654761 | HCID 43654761 | — |
Reaction Steps
The title compound was prepared by palladium-catalyzed arylation of 2,4-dichloropyrimidine and 4-trifluoromethoxyphenyl boronic acid: mp 70-73° C.; 1H NMR (400 MHz, CDCl3) δ 8.68 (d, J=5.6 Hz, 1H), 8.16 (d, J=9.1 Hz, 2H), 7.65 (d, J=5.3 Hz, 1H), 7.36 (dd, J=9.2, 0.9 Hz, 2H); EIMS m/z 274 (M+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08680269B2 |
| Source dataset | uspto-grants-2014_03 |
| ORD ID | ord-aec2ab62610842338db346ff2a4e766d |
| Source note | uspto-grants-2014_03 |