HuagongsheHuagongshe Chemistry Print Report · For research reference only
2,6-Dichloropyrazine → HCID 57824459, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2,6-Dichloropyrazine | HCID 78504 | — |
| Reactant | 4-(Trifluoromethoxy)phenylboronic acid | HCID 2734386 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Product | HCID 57824459 | HCID 57824459 | — |
Reaction Steps
The compound was prepared by palladium-catalyzed arylation of 2,6-dichloropyrazine and 4-trifluoromethoxyphenyl boronic acid: mp 58-60° C.; 1H NMR (400 MHz, CDCl3) δ 8.94 (s, 1H), 8.57 (s, 1H), 8.10 (d, J=9.0 Hz, 2H), 7.37 (d, J=8.4 Hz, 2H); EIMS m/z 274 (M+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08680269B2 |
| Source dataset | uspto-grants-2014_03 |
| ORD ID | ord-55afd828cbac468bac187357c91f0145 |
| Source note | uspto-grants-2014_03 |