HuagongsheHuagongshe Chemistry Print Report · For research reference only
Pentanal, 5,5-dimethoxy- → (E)-7-(4-chlorophenyl)-6-nitrohept-5-enal
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Pentanal, 5,5-dimethoxy- | HCID 170903 | — |
| Reactant | 1-(4-Chlorophenyl)-2-nitroethane | HCID 11469495 | — |
| Solvent | Ethyl acetate hexane | HCID 21226206 | — |
| Product | (E)-7-(4-chlorophenyl)-6-nitrohept-5-enal | HCID 25187598 | 45.1% |
Reaction Steps
Prepared according to the general procedure B from 1-chloro-4-(2-nitroethyl)benzene 112g (24 mmol) and 5,5-dimethoxypentanal 131 (16 mmol) to provide the title compound as yellow oil (1.93 g, 45% yield) after silica gel chromatography (EtOAc/Hexane).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08680335B2 |
| Source dataset | uspto-grants-2014_03 |
| ORD ID | ord-2115f4463445473aac43aa1448f0dd0b |
| Source note | uspto-grants-2014_03 |